Bio-Path Holdings Updates Clinical Trial Data and it Sounds Promising

First, congratulations to those who received our text alert and followup email update on January 23rd, 2019 while BPTH was trading at $2.00 – $2.10/share. https://tradersnewssource.com/nasdaq-bpth-low-float-breakout-alert/

Bio-Path Holdings, Inc. (NASDAQ: BPTH) operates as a clinical and preclinical stage oncology focused RNAi nano particle drug development company in the United States. The company develops products based on DNAbilize, a drug delivery and antisense technology that uses P-ethoxy, which is a deoxyribonucleic acid (DNA) backbone modification intended to protect the DNA from destruction.

Recent Events

March 06, 2019. Bio-Path today announces a clinical update to the previously reported interim analysis from the Phase 2 trial of prexigebersen (BP1001) for the treatment of acute myeloid leukemia (AML) and provides its plans for the compound’s clinical development moving forward toward registration.

In April 2018, Bio-Path completed an initial interim analysis of 17 evaluable patients from Stage 1 of the Phase 2 study.  These results showed a promising safety and efficacy profile with 47% of patients having a response comprised of four complete response (CR) patients, including one CRi (complete response with incomplete hematologic recovery) and four patients with stable disease. https://finance.yahoo.com/news/bio-path-announces-clinical-interim-130000716.html

Products

DNAbilize® antisense RNAi nanoparticle technology to develop a portfolio of targeted nucleic acid cancer drugs.

Its lead drug candidate is prexigebersen, which is in Phase II clinical trials for the treatment of acute myeloid leukemia and chronic myelogenous leukemia; and in preclinical studies for solid tumors, including breast cancer and ovarian cancer. The company is also developing Liposomal Bcl2 for the treatment of lymphoma; and Liposomal Stat3 that is in preclinical stage for the treatment of pancreatic cancer.

About

Bio-Path Holdings, Inc. operates as a clinical and preclinical stage oncology focused RNAi nano particle drug development company in the United States. The company develops products based on DNAbilize, a drug delivery and antisense technology that uses P-ethoxy, which is a deoxyribonucleic acid (DNA) backbone modification intended to protect the DNA from destruction. Its lead drug candidate is prexigebersen, which is in Phase II clinical trials for the treatment of acute myeloid leukemia and chronic myelogenous leukemia; and in preclinical studies for solid tumors, including breast cancer and ovarian cancer. The company is also developing Liposomal Bcl2 for the treatment of lymphoma; and Liposomal Stat3 that is in preclinical stage for the treatment of pancreatic cancer. It has license agreement with The University of Texas relating to the delivery technology platform for antisense nucleic acids, including two single nucleic acid drug products. Bio-Path Holdings, Inc. was founded in 2007 and is based in Bellaire, Texas.

Financial review

Bio-Path Holdings reported a loss of $3.1 million in its third quarter 2018. On a per-share basis, the Bellaire, Texas-based company said it had a loss of 27 cents.

Stock influences and risk factors

Continuing positive data from clinical trials could act as a catalyst for the company’s shares.

They will continue to require substantial additional capital for the foreseeable future.

The pharmaceutical and biotechnology industry is highly competitive. If they are unable to compete effectively, their drug candidates may be rendered noncompetitive or obsolete.

They are increasingly dependent on information technology systems to operate the business and a cyber-attack or other breach of systems, or those of third parties on whom they may rely, could subject them to liability or interrupt the operation of business.

Stock chart

On Wednesday, March 7, 2019, BPTH shares were at $12.28 (+166%) on traded volume of 49.6M shares. The current RSI (14) is 78.59


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