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For too long, chronic pain has meant choosing between suffering and the dangerous trade-off of opioids. At Alyea Therapeutics, we are changing that equation with non-opioid alternatives.

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Opioids have long been the default for chronic pain, despite their devastating consequences. At Alyea Therapeutics, our mission is clear: to end dependence on opioids by providing a safer, science-backed alternative.

With our investigational Low Dose Naltrexone (LDN), we are pioneering a new era in pain management for patients suffering from Complex Regional Pain Syndrome (CRPS)–one where lasting relief doesn’t come at the cost of addiction.

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At Alyea Therapeutics, our work is driven by a commitment to safety, innovation, and impact. We are not just developing treatments–we are reshaping the future of pain management to eliminate opioid dependence and improve lives.

Innovative Science

Patient-First Approach

Redefining Pain Management

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Dr. Amol Soin is a quadruple board-certified pain specialist and a pioneer in non-opioid pain treatments. A nationally recognized leader, he has dedicated his career to developing safer, more effective alternatives to opioids.

Founder of multiple biotech companies and holder of several pain treatment patents

Published extensively in peer-reviewed medical journals

Former President of the Ohio Medical Board, shaping opioid crisis regulations

Leader in pain medicine, serving as President of top industry organizations

Faculty positions at three medical schools

Dr. Soin’s expertise and dedication fuel Alyea’s mission to break the link between chronic pain and opioid dependence.

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Low Dose Naltrexone

An investigational next-generation, non-opioid treatment, LDN targets inflammation and pain pathways to provide lasting relief without addiction risks.

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Alyea Clear Patch

A next-generation topical pain relief technology, designed for targeted, non-invasive treatment with strong market potential.

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