APPROVED USE FOR AEMCOLO

Aemcolo is for the treatment of adults with Travelers’ Diarrhea caused by certain types of bacteria called E. coli.

Wherever your journey takes you, pack Aemcolo

What is Travelers’ Diarrhea?

Sudden onset of painful stomach cramps, loose or watery stools, nausea, vomiting, and gas can be symptoms of Travelers’ Diarrhea, which can last from a few hours to several days.

Travelers’ Diarrhea can ruin your plans

Travelers’ Diarrhea can be caused by viruses and parasites, but it is usually caused by the bacteria Escherichia coli (E. coli) found in contaminated food and drink. Being careful may not be enough…even sipping a drink with contaminated ice or brushing your teeth with tap water in some regions can infect you with E. coli.

Is your destination high-risk?

You can get Travelers’ Diarrhea anywhere, but you’re more at risk in certain parts of the globe. Without treatment, symptoms can last a week or more, ruining your plans.

Source: Adapted from Steffen/Hill/DuPont, JAMA 2015

Why pack Aemcolo?

Whether your trip is for a business meeting or your bucket list, you’ve invested significant time, energy and expense into planning.

If you get Travelers’ Diarrhea abroad, you may not get the appropriate treatment if you don’t speak or read the language. Finding local healthcare could be difficult and expensive, too.

Don‘t let Travelers’ Diarrhea derail your next adventure. Pack Aemcolo.

Up to 70% of travelers to medium-to-high-risk countries may be affected by travelers’ diarrhea…

Source: Centers for Disease Control Yellow Book 2020: Health Information
for International Travel

What is
Aemcolo?

Aemcolo is a targeted, prescription antibiotic that acts fast to kill E. coli:

  • Short, 3-day treatment
  • Take Aemcolo only after diarrhea symptoms begin, and you strongly suspect they are caused by a bacterial infection.

In a clinical study, Aemocolo showed:

  • 22 hours faster symptom relief than placebo
  • 81% of patients cured within 3 days

Aemcolo uses MMX® technology, a special coating that delays release of the medication until it reaches the sites of infection. The result is a targeted release of medicine where it is needed.

Anyone can get Travelers' Diarrhea

Higher risk travelers include those with certain conditions or on medications which can affect the body’s natural defenses, such as:

  • Diabetes
  • Pre-existing stomach disorders
  • Weakened immune systems
  • Regular use of acid blockers or antacids
  • Inflammatory bowel disease
  • Cirrhosis of the liver

How is Aemcolo
Different?

Systemic antibiotics such as azithromycin and ciprofloxacin, which are traditionally used to treat Travelers’ Diarrhea, are not targeted and circulate throughout your body, carrying a risk of drug-to-drug interactions with many common regular medications, such as some blood thinners, COPD or asthma medications, muscle relaxers and even certain antacids.

Do you take regular medications?

According to the CDC Yellow Book, up to 45% of travelers on chronic medications are at risk for drug-to-drug interactions with systemic antibiotics.

Aemcolo is nonsystemic and only releases the medication where it’s needed at the sites of infection, not throughout your system.

Aemcolo benefits include:

  • Nonsystemic, which lowers the risk of drug interactions
  • Low rates of side effects
  • Delivers medication to the specific sites of infection

Talk to your healthcare professional
about Aemcolo before you travel.

An Aemcolo study of 264 adult patients traveling to Guatemala and Mexico showed:

22 hours
Faster symptom relief than placebo
81% of patients
cured within 3 days

Source: Aemcolo Prescribing Information

Dosing and safety

Take Aemcolo only after diarrhea symptoms begin, and you strongly suspect they are caused by a bacterial infection. Follow your provider’s recommendations, but the usual dose of Aemcolo is 2 tablets by mouth, 2 times a day (in the morning and evening) for 3 days.

  • Aemcolo tablets should be swallowed whole with a full glass of water and not chewed, crushed, or broken
  • Aemcolo may be taken with or without food but must not be taken with alcohol

It is important to take the antibiotic exactly as directed. Do not skip doses or end before all the medication is taken. If you do, you may lower how well the drug will work and may increase the chance of the bacteria becoming resistant.

Stop taking Aemcolo if diarrhea gets worse or lasts more than 48 hours and notify your healthcare provider.

Most common side effects

In Aemcolo clinical trials:

  • The most common side effects were constipation (3.5% vs 1.5% placebo) and headache (3.3% vs 1.9% ciprofloxacin)
  • Discontinuation due to side effects occurred in 1% of patients

Keep Aemcolo in your travel kit in case Travelers’ Diarrhea strikes.

Simple Dosing

2 Tablets

Twice daily

For 3 days