A Non-invasive Focused Extracorporeal Shock Wave Therapy System Promotes Increased Tissue Oxygen Saturation in Chronic Wounds in Persons with Diabetes

Windy Cole; Stacey Coe; Greg Maislin; Valerie Marmolejo

doi:doi:10.11648/j.ajns.20211003.14

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A Non-invasive Focused Extracorporeal Shock Wave Therapy System Promotes Increased Tissue Oxygen Saturation in Chronic Wounds in Persons with Diabetes

Windy Cole, Stacey Coe, Greg Maislin, Valerie Marmolejo

Published in American Journal of Nursing Science (Volume 10, Issue 3)

Received: 27 April 2021 Accepted: 8 May 2021 Published: 20 May 2021

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Abstract

Diabetes affects 30.3 million Americans and is on the rise. Chronic lower extremity ulceration in patients with diabetes is a common complication that can lead to major morbidity and mortality if not addressed expeditiously. Despite numerous advances in wound care and healing over the past two decades, these ulcerations continue to pose a significant clinical problem. This case series aimed to evaluate the effectiveness of focused extracorporeal shock wave therapy (F-ESWT) administered via a pulsed acoustic cellular expression system in enhancing localized wound tissue oxygenation and perfusion in chronic wounds. Fifteen subjects with a history of diabetes and a chronic wound of the foot or ankle that had failed to achieve wound area reduction of 50% or greater after at least 4 weeks of standard of care treatment underwent four weekly treatments of F-ESWT administered via a pulsed acoustic cellular expression system. Near-infrared spectroscopy (NIRS) was used to determine the effectiveness of F-ESWT on tissue oxygen saturation within the wound bed. All subjects demonstrated a statistically significant increase in tissue oxygen saturation within the wound bed as well as a decrease in wound area. Seven wounds healed. Results of this case study suggest that F-ESWT promotes increased tissue oxygenation within the wound bed and neovascularization, potentially facilitating accelerated wound resolution of chronic lower extremity ulcerations in patients with diabetes.

Published in	American Journal of Nursing Science (Volume 10, Issue 3)
DOI	10.11648/j.ajns.20211003.14
Page(s)	156-162
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Extracorporeal Shock Wave Therapy, Diabetic feet, Diabetic Foot Ulcer, Angiogenesis, Spectroscopy, Near-Infrared, Oxygenation, Oxygenated Hemoglobin, Neovascularization

References

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APA Style

Windy Cole, Stacey Coe, Greg Maislin, Valerie Marmolejo. (2021). A Non-invasive Focused Extracorporeal Shock Wave Therapy System Promotes Increased Tissue Oxygen Saturation in Chronic Wounds in Persons with Diabetes. American Journal of Nursing Science, 10(3), 156-162. https://doi.org/10.11648/j.ajns.20211003.14

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ACS Style

Windy Cole; Stacey Coe; Greg Maislin; Valerie Marmolejo. A Non-invasive Focused Extracorporeal Shock Wave Therapy System Promotes Increased Tissue Oxygen Saturation in Chronic Wounds in Persons with Diabetes. Am. J. Nurs. Sci. 2021, 10(3), 156-162. doi: 10.11648/j.ajns.20211003.14

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AMA Style

Windy Cole, Stacey Coe, Greg Maislin, Valerie Marmolejo. A Non-invasive Focused Extracorporeal Shock Wave Therapy System Promotes Increased Tissue Oxygen Saturation in Chronic Wounds in Persons with Diabetes. Am J Nurs Sci. 2021;10(3):156-162. doi: 10.11648/j.ajns.20211003.14

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@article{10.11648/j.ajns.20211003.14,
  author = {Windy Cole and Stacey Coe and Greg Maislin and Valerie Marmolejo},
  title = {A Non-invasive Focused Extracorporeal Shock Wave Therapy System Promotes Increased Tissue Oxygen Saturation in Chronic Wounds in Persons with Diabetes},
  journal = {American Journal of Nursing Science},
  volume = {10},
  number = {3},
  pages = {156-162},
  doi = {10.11648/j.ajns.20211003.14},
  url = {https://doi.org/10.11648/j.ajns.20211003.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajns.20211003.14},
  abstract = {Diabetes affects 30.3 million Americans and is on the rise. Chronic lower extremity ulceration in patients with diabetes is a common complication that can lead to major morbidity and mortality if not addressed expeditiously. Despite numerous advances in wound care and healing over the past two decades, these ulcerations continue to pose a significant clinical problem. This case series aimed to evaluate the effectiveness of focused extracorporeal shock wave therapy (F-ESWT) administered via a pulsed acoustic cellular expression system in enhancing localized wound tissue oxygenation and perfusion in chronic wounds. Fifteen subjects with a history of diabetes and a chronic wound of the foot or ankle that had failed to achieve wound area reduction of 50% or greater after at least 4 weeks of standard of care treatment underwent four weekly treatments of F-ESWT administered via a pulsed acoustic cellular expression system. Near-infrared spectroscopy (NIRS) was used to determine the effectiveness of F-ESWT on tissue oxygen saturation within the wound bed. All subjects demonstrated a statistically significant increase in tissue oxygen saturation within the wound bed as well as a decrease in wound area. Seven wounds healed. Results of this case study suggest that F-ESWT promotes increased tissue oxygenation within the wound bed and neovascularization, potentially facilitating accelerated wound resolution of chronic lower extremity ulcerations in patients with diabetes.},
 year = {2021}
}

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TY  - JOUR
T1  - A Non-invasive Focused Extracorporeal Shock Wave Therapy System Promotes Increased Tissue Oxygen Saturation in Chronic Wounds in Persons with Diabetes
AU  - Windy Cole
AU  - Stacey Coe
AU  - Greg Maislin
AU  - Valerie Marmolejo
Y1  - 2021/05/20
PY  - 2021
N1  - https://doi.org/10.11648/j.ajns.20211003.14
DO  - 10.11648/j.ajns.20211003.14
T2  - American Journal of Nursing Science
JF  - American Journal of Nursing Science
JO  - American Journal of Nursing Science
SP  - 156
EP  - 162
PB  - Science Publishing Group
SN  - 2328-5753
UR  - https://doi.org/10.11648/j.ajns.20211003.14
AB  - Diabetes affects 30.3 million Americans and is on the rise. Chronic lower extremity ulceration in patients with diabetes is a common complication that can lead to major morbidity and mortality if not addressed expeditiously. Despite numerous advances in wound care and healing over the past two decades, these ulcerations continue to pose a significant clinical problem. This case series aimed to evaluate the effectiveness of focused extracorporeal shock wave therapy (F-ESWT) administered via a pulsed acoustic cellular expression system in enhancing localized wound tissue oxygenation and perfusion in chronic wounds. Fifteen subjects with a history of diabetes and a chronic wound of the foot or ankle that had failed to achieve wound area reduction of 50% or greater after at least 4 weeks of standard of care treatment underwent four weekly treatments of F-ESWT administered via a pulsed acoustic cellular expression system. Near-infrared spectroscopy (NIRS) was used to determine the effectiveness of F-ESWT on tissue oxygen saturation within the wound bed. All subjects demonstrated a statistically significant increase in tissue oxygen saturation within the wound bed as well as a decrease in wound area. Seven wounds healed. Results of this case study suggest that F-ESWT promotes increased tissue oxygenation within the wound bed and neovascularization, potentially facilitating accelerated wound resolution of chronic lower extremity ulcerations in patients with diabetes.
VL  - 10
IS  - 3
ER  -

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Author Information

Windy Cole

College of Podiatric Medicine, Kent State University, Independence, the United States
Stacey Coe

College of Podiatric Medicine, Kent State University, Independence, the United States
Greg Maislin

Biomedical Statistical Consulting, Wynnewood, the United States
Valerie Marmolejo

Scriptum Medica, University Place, Washington, the United States

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APA Style

Windy Cole, Stacey Coe, Greg Maislin, Valerie Marmolejo. (2021). A Non-invasive Focused Extracorporeal Shock Wave Therapy System Promotes Increased Tissue Oxygen Saturation in Chronic Wounds in Persons with Diabetes. American Journal of Nursing Science, 10(3), 156-162. https://doi.org/10.11648/j.ajns.20211003.14

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ACS Style

Windy Cole; Stacey Coe; Greg Maislin; Valerie Marmolejo. A Non-invasive Focused Extracorporeal Shock Wave Therapy System Promotes Increased Tissue Oxygen Saturation in Chronic Wounds in Persons with Diabetes. Am. J. Nurs. Sci. 2021, 10(3), 156-162. doi: 10.11648/j.ajns.20211003.14

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AMA Style

Windy Cole, Stacey Coe, Greg Maislin, Valerie Marmolejo. A Non-invasive Focused Extracorporeal Shock Wave Therapy System Promotes Increased Tissue Oxygen Saturation in Chronic Wounds in Persons with Diabetes. Am J Nurs Sci. 2021;10(3):156-162. doi: 10.11648/j.ajns.20211003.14

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@article{10.11648/j.ajns.20211003.14,
  author = {Windy Cole and Stacey Coe and Greg Maislin and Valerie Marmolejo},
  title = {A Non-invasive Focused Extracorporeal Shock Wave Therapy System Promotes Increased Tissue Oxygen Saturation in Chronic Wounds in Persons with Diabetes},
  journal = {American Journal of Nursing Science},
  volume = {10},
  number = {3},
  pages = {156-162},
  doi = {10.11648/j.ajns.20211003.14},
  url = {https://doi.org/10.11648/j.ajns.20211003.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajns.20211003.14},
  abstract = {Diabetes affects 30.3 million Americans and is on the rise. Chronic lower extremity ulceration in patients with diabetes is a common complication that can lead to major morbidity and mortality if not addressed expeditiously. Despite numerous advances in wound care and healing over the past two decades, these ulcerations continue to pose a significant clinical problem. This case series aimed to evaluate the effectiveness of focused extracorporeal shock wave therapy (F-ESWT) administered via a pulsed acoustic cellular expression system in enhancing localized wound tissue oxygenation and perfusion in chronic wounds. Fifteen subjects with a history of diabetes and a chronic wound of the foot or ankle that had failed to achieve wound area reduction of 50% or greater after at least 4 weeks of standard of care treatment underwent four weekly treatments of F-ESWT administered via a pulsed acoustic cellular expression system. Near-infrared spectroscopy (NIRS) was used to determine the effectiveness of F-ESWT on tissue oxygen saturation within the wound bed. All subjects demonstrated a statistically significant increase in tissue oxygen saturation within the wound bed as well as a decrease in wound area. Seven wounds healed. Results of this case study suggest that F-ESWT promotes increased tissue oxygenation within the wound bed and neovascularization, potentially facilitating accelerated wound resolution of chronic lower extremity ulcerations in patients with diabetes.},
 year = {2021}
}

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TY  - JOUR
T1  - A Non-invasive Focused Extracorporeal Shock Wave Therapy System Promotes Increased Tissue Oxygen Saturation in Chronic Wounds in Persons with Diabetes
AU  - Windy Cole
AU  - Stacey Coe
AU  - Greg Maislin
AU  - Valerie Marmolejo
Y1  - 2021/05/20
PY  - 2021
N1  - https://doi.org/10.11648/j.ajns.20211003.14
DO  - 10.11648/j.ajns.20211003.14
T2  - American Journal of Nursing Science
JF  - American Journal of Nursing Science
JO  - American Journal of Nursing Science
SP  - 156
EP  - 162
PB  - Science Publishing Group
SN  - 2328-5753
UR  - https://doi.org/10.11648/j.ajns.20211003.14
AB  - Diabetes affects 30.3 million Americans and is on the rise. Chronic lower extremity ulceration in patients with diabetes is a common complication that can lead to major morbidity and mortality if not addressed expeditiously. Despite numerous advances in wound care and healing over the past two decades, these ulcerations continue to pose a significant clinical problem. This case series aimed to evaluate the effectiveness of focused extracorporeal shock wave therapy (F-ESWT) administered via a pulsed acoustic cellular expression system in enhancing localized wound tissue oxygenation and perfusion in chronic wounds. Fifteen subjects with a history of diabetes and a chronic wound of the foot or ankle that had failed to achieve wound area reduction of 50% or greater after at least 4 weeks of standard of care treatment underwent four weekly treatments of F-ESWT administered via a pulsed acoustic cellular expression system. Near-infrared spectroscopy (NIRS) was used to determine the effectiveness of F-ESWT on tissue oxygen saturation within the wound bed. All subjects demonstrated a statistically significant increase in tissue oxygen saturation within the wound bed as well as a decrease in wound area. Seven wounds healed. Results of this case study suggest that F-ESWT promotes increased tissue oxygenation within the wound bed and neovascularization, potentially facilitating accelerated wound resolution of chronic lower extremity ulcerations in patients with diabetes.
VL  - 10
IS  - 3
ER  -

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