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The Opioid Crisis: Opioid Overdose is the Leading Cause of Death Among 18-45 Year-Olds*

Significant Unmet Need for Safe and Effective Non-Opioid Pain Therapies

*Centers for Disease Control and Prevention

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Highly Targeted Therapies Delivered Exclusively to the Pain Location

We are advancing an elegantly designed, highly potent, locally-administered, disease-modifying, non-opioid analgesic gene therapy for the treatment of chronic pain.

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Lead Program:
Chronic
Osteoarthritis
Knee Pain

Degenerative joint disease characterized by the breakdown of cartilage in the joints, leading to pain and stiffness

Erythromelalgia

Rare hereditary condition that causes pain, burning and redness primarily in the feet but also other extremities
Video Player

The Opioid Crisis: Opioid Overdose is the Leading Cause of Death Among 18-45 Year-Olds*

Significant Unmet Need for Safe and Effective Non-Opioid Pain Therapies

*Centers for Disease Control and Prevention

Video Player

Highly Targeted Therapies Delivered Exclusively to the Pain Location

We are advancing an elegantly designed, highly potent, locally-administered, disease-modifying, non-opioid analgesic gene therapy for the treatment of chronic pain.

Video Player
Video Player

Lead Program:
Chronic
Osteoarthritis
Knee Pain

Degenerative joint disease characterized by the breakdown of cartilage in the joints, leading to pain and stiffness

Erythromelalgia

Rare hereditary condition that causes pain, burning and redness primarily in the feet but also other extremities
Video Player

Our Innovation Along Two Key Dimensions to Realize a Truly Novel Approach to Chronic Pain Treatment Designed to Avoid Systemic Side-Effects

Novel CA8* Therapeutic Protein/Transgene That Acts Inside of Pain-Sensing Nerves (Fibers)

(Analgesic Protein that works within the sensory neuron)  more+

The Challenge: Selectively Delivering This Peptida Directly Inside These Affected Nerve Fibers To Minimize Systemic Exposure.

Novel Gene Therapy Approach Delivers Our Proprietary CA8* Analgesic Peptide to the Inside of Affected Pain Fibers

(Highly specific viral vector, non-replicating, with excellent safety profile)  more+

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Our Next Generation Pain Treatment Pipeline

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NEWS

LATEST NEWS