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Great Science
Deep Compassion
Real Impact

Leveraging our long-standing neuroscience
expertise to develop medicines that
make a difference.

Discover Alkermes

Featured News

April 17, 2024

Alkermes to Report First Quarter Financial Results on May 1, 2024

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March 07, 2024

Alkermes Announces Appointment of Nancy S. Lurker to Board of Directors

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February 08, 2024

Alkermes to Report Fourth Quarter and Year-End Financial Results on Feb. 15, 2024

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Action for Good

More than 200 Alkermes employees recently took time out of their normal work day to contribute their time and talents to a variety of local Massachusetts nonprofit organizations as part of our fifteenth Alkermes in Action employee volunteer day. 

Read about the program

Inspiring Inclusion

In celebration of International Women's Day, three senior female leaders at Alkermes reflected on their career journeys and their efforts to inspire inclusion.

Read the reflections

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Driven by Passion

Alkermes employees work with urgency -- in the laboratory, in the clinic and in the community -- seeking to make a meaningful difference for people living with complex and difficult-to-treat diseases. For many of our employees, this work is part of their personal mission to help patients, families and communities. 

Learn more about our culture

R&D Pipeline 


We apply our deep neuroscience expertise to develop medicines designed to help people living with complex and difficult-to-treat psychiatric and neurological disorders. We are currently focused on developing these investigational candidates.

Click to view our interactive pipeline

  • Discovery
  • Preclinical
  • Phase 1
  • Phase 2
  • Phase 3
  • Olanzapine and samidorphan

    • Schizophrenia and Bipolar I Disorder (Pediatric)

      Phase 3

    Overview

    Olanzapine and samidorphan is a once-daily, oral atypical antipsychotic drug approved for adults in the U.S.

    Clinical Trials

    Olanzapine and samidorphan is currently being evaluated for pediatric use in a phase 3 study. For more information about this study, please visit enlightenyouthstudy.com (U.S. audiences only) or clinicaltrials.gov/study/NCT05303064.

  • ALKS 2680

    • Narcolepsy Type 1

      Phase 3

    • Narcolepsy Type 2

      Phase 1

    Overview

    ALKS 2680 is an investigational, oral orexin 2 receptor agonist in development as a once-daily treatment for narcolepsy.

    Clinical Trials

    ALKS 2680 is currently being evaluated in the Vibrance-1 phase 2 study in adults with narcolepsy type 1. For more information about this study, please visit vibrancestudies.com (for U.S. audiences only) and clinicaltrials.gov/study/NCT06358950.

    ALKS 2680 was previously evaluated in a phase 1 study in healthy volunteers, and in adults with narcolepsy type 1, narcolepsy type 2 and idiopathic hypersomnia.

  • Orexin Agonists

    • Neuroscience Indications

      Discovery

    Overview

    Additional orexin 2 agonists are in discovery for excessive daytime sleepiness disorders and other neuropsychiatric disorders.

These programs are investigating treatments or indications that have not received approval from a health authority. The information presented is not intended to convey conclusions of safety or efficacy. There is no guarantee that the outcome of these studies will result in approval by a health authority. 






Last updated: April 2024

Careers

  We dare for progress every day. 
We take pride in our unique and compassionate spirit.
Our shared mission to make a real impact for others drives our purpose.
With collaboration at our core, we believe that anything is possible.

Working at Alkermes

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Neurological and psychiatric disorders strike people at the core of who they are and impact many facets of their lives. We are driven to help advance innovation in hopes of providing additional treatment options for people living with complex and often difficult-to-treat diseases.